28 April 1611. The Pontifical and Royal University of Santo Tomas - Catholic University of the Philippines, reputed to be Asia's oldest existing university, is established by Miguel de Benavides with the blessings of King Philip II. Originally named Colegio de Nuestra Señora del Santísimo Rosario and later Colegio de Santo Tomas, it officially became a university on 20 November 1645. More about the school here.
According to a UST discussion group, the school's alumni include former presidents (Emilio Aguinaldo, Manuel Quezon, Sergio Osmeña) national heroes (Jose Rizal, Marcelo H. del Pilar, Mariano Gomez, Jose Apolonio Burgos, and Jacinto Zamora), and famous media personalities and/or writers (Francisco Sionil Jose, Cristina Pantoja-Hidalgo, Bienvenido Lumbera, Cirilo Bautista, Ophelia Alcantara Dimalanta, Eugenia "Eggie" Apostol, Ramon Francisco, Isabel de Leon, Lourd Ernest Hanopol de Veyra, Lito Zulueta, Jullie Yap-Daza, Nerisa Guevara, Michael Coroza, Jose Wendell-Capili, Nick Joaquin, Angelo Suarez, Carlomar Daoana, Vim Nadera, Rina Jimenez-David, Arnold Clavio).